Reported incidents of the use of nutritional supplements containing deer antler velvet by athletes has increased significantly in recent years. The supplements have been reported to contain insulin-like growth factor-1 (IGF-1), which is a banned substance included on the World Anti-Doping Agency (WADA) prohibited list. The presence of deer and human IGF-1 was tested in six commercially available supplements. 


The peak area from each MRM transition was used to calculate the product ion ratios relative to the most abundant transition. Product ion ratios measured in the supplements were matched to ratios measured in purified protein standards. A match to human IGF-1 was identified for all the MRM transitions measured in four of the supplements tested.


The presence of a pharmaceutical protein, human IGF-1, was confirmed in four commercially available products sold as all natural, nutritional supplements. These methods can be used to screen additional products to further prevent the illegal sale of adulterated supplements. Copyright © 2013 John Wiley & Sons, Ltd.

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Velvet antler has been used for over two thousand years in ancient Eastern medicine and is only second to ginseng in importance for the mainstay of Traditional Chinese Medicine. 

Thousands of papers have been published on the composition and biochemical effects of velvet antler and its constituents. Velvet antler has uses ranging from safe anti-aging solutions to enhancing the performance of many elite athletes.

MDgenesis's products are not synthetically derived IGF-1. Instead, our exclusive 43:1 velvet antler extract is comprised of 90% protein. The active ingredients found in velvet antler include growth factors, minerals and trace mineral elements, protein, collagen and lipids, and glycosaminoglycans.

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