RATIONALE 

Reported incidents of the use of nutritional supplements containing deer antler velvet by athletes has increased significantly in recent years. The supplements have been reported to contain insulin-like growth factor-1 (IGF-1), which is a banned substance included on the World Anti-Doping Agency (WADA) prohibited list. The presence of deer and human IGF-1 was tested in six commercially available supplements. 

RESULTS 

The peak area from each MRM transition was used to calculate the product ion ratios relative to the most abundant transition. Product ion ratios measured in the supplements were matched to ratios measured in purified protein standards. A match to human IGF-1 was identified for all the MRM transitions measured in four of the supplements tested.

CONCLUSIONS

The presence of a pharmaceutical protein, human IGF-1, was confirmed in four commercially available products sold as all natural, nutritional supplements. These methods can be used to screen additional products to further prevent the illegal sale of adulterated supplements. Copyright © 2013 John Wiley & Sons, Ltd.

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INTRODUCTION

In the present study, we investigated the physiological and potential performance enhancing effects of New Zealand Deer Antler Velvet (NZDAV) supplementation in men. Deer antler velvet reportedly enhances immune function, improves athletic performance, muscle recovery after exercise, enhances sexual functioning in both men and women, improves disease recovery, enhances cardiovascular function, and may be a superior source of insulin-like-growth factors for manufacturers. While there have been several studies aimed specifically at the potential health benefits of deer antler velvet using in-vitro and in- vivo animal research models (Clifford et al. 1979; Wang et al. 1988a; Wang et al. 1988b; Zhang et al. 1994; Zhou et al. 1999; Allen et al. 2002), to date there are no published placebo controlled human clinical trials on physiological function and performance. Thus, the primary purpose of this study was to investigate what effects 1350 mg of NZDAV supplementation twice a day had on body composition, maximal strength, maximal aerobic power, and maximal power output before and after 10 weeks of resistance training in men aged 18 to 35 years old. In addition, comprehensive blood profiles were taken to evaluate if any detrimental effects occurred over the 10-week treatment period in blood lipids, and liver and kidney function.

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INTRODUCTION

Velvet antler has been used for over two thousand years in ancient Eastern medicine and is only second to ginseng in importance for the mainstay of Traditional Chinese Medicine. 

Thousands of papers have been published on the composition and biochemical effects of velvet antler and its constituents. Velvet antler has uses ranging from safe anti-aging solutions to enhancing the performance of many elite athletes.

MDgenesis's products are not synthetically derived IGF-1. Instead, our exclusive 43:1 velvet antler extract is comprised of 90% protein. The active ingredients found in velvet antler include growth factors, minerals and trace mineral elements, protein, collagen and lipids, and glycosaminoglycans.

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