INTRODUCTION

Sarcopenia is the loss of muscle mass and strength that occurs with advancing age [1]. Although definitions (and therefore estimates of prevalence) vary, it is widely recognised as a common condition among older adults, and one that is associated with huge personal and financial costs [1, 2]. Declining muscle mass and strength are expected components of ageing. However, the rate of decline differs across the population [1, 3], suggesting that modifiable behavioural factors such as diet and lifestyle may be important influences on muscle function in older age. This paper considers the evidence that links diet to muscle mass and strength, and implications for strategies to prevent or delay sarcopenia in older age. Read More

BACKGROUND

Much interest has been focused on nutritional treatment of sarcopenia, loss of muscle mass and performance associated to aging; however, its benefits are unclear.

OBJECTIVE

To analyze the relevance of nutritional treatment of sarcopenia and assess the effects of supplementation on muscle mass and function within the aged population.

CONCLUSION

Nutritional supplementation is effective in the treatment of sarcopenia in old age, and its positive effects increase when associated with physical exercise. The main limitation of this treatment is lack of long-term adherence. A healthy diet associated with a physically active lifestyle and possibly with aerobic exercise are the basis of healthy aging, which is the aim of all doctors treating aged people must seek.

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RATIONALE 

Reported incidents of the use of nutritional supplements containing deer antler velvet by athletes has increased significantly in recent years. The supplements have been reported to contain insulin-like growth factor-1 (IGF-1), which is a banned substance included on the World Anti-Doping Agency (WADA) prohibited list. The presence of deer and human IGF-1 was tested in six commercially available supplements. 

RESULTS 

The peak area from each MRM transition was used to calculate the product ion ratios relative to the most abundant transition. Product ion ratios measured in the supplements were matched to ratios measured in purified protein standards. A match to human IGF-1 was identified for all the MRM transitions measured in four of the supplements tested.

CONCLUSIONS

The presence of a pharmaceutical protein, human IGF-1, was confirmed in four commercially available products sold as all natural, nutritional supplements. These methods can be used to screen additional products to further prevent the illegal sale of adulterated supplements. Copyright © 2013 John Wiley & Sons, Ltd.

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INTRODUCTION

Velvet antler has been used for over two thousand years in ancient Eastern medicine and is only second to ginseng in importance for the mainstay of Traditional Chinese Medicine. 

Thousands of papers have been published on the composition and biochemical effects of velvet antler and its constituents. Velvet antler has uses ranging from safe anti-aging solutions to enhancing the performance of many elite athletes.

MDgenesis's products are not synthetically derived IGF-1. Instead, our exclusive 43:1 velvet antler extract is comprised of 90% protein. The active ingredients found in velvet antler include growth factors, minerals and trace mineral elements, protein, collagen and lipids, and glycosaminoglycans.

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